Posttransplantation lymphoproliferative disorder involving liver after renal transplantation

Posttransplantation lymphoproliferative disorder (PTLD) is a serious complication following solid organ transplantation. Most of PTLD is related to an interaction of Epstein-Barr virus (EBV) infection and immune suppression. PTLD occurs most common after intestine transplantation and the least common after renal transplantation. PTLD can involve any organs. Abdominal organs are frequently involved, and up to 50% of all cases of PTLD are confined to the abdomen. The disease manifestation and the anatomic pattern of organ involvement is highly dependent on the type of transplantation. To provide more detailed understanding of hepatic involvement of PTLD, here a case of PTLD involving liver after renal transplantation is presented with radiological imaging findings. A review about classification and clinical considerations and the imaging features of PTLD involving liver will be discussed. Familiarity with the imaging findings of this disorder can help early and accurate diagnosis and result in better prognosis.